Microbial Genome

Introduction

Bacterial genome equipped with the characteristics of relatively small, high repeat sequence and prone to gene mutation. Fungal genomics is a scientific discipline that concerns the genome, encompassing the entire hereditary information, of fungi. Using whole genome de novo sequencing, a bacterium or fungi whose genome sequence or genomic information of a related species is unknown can be completely obtanied by sequencing, splicing and assembling. 
With the development of High-throughput sequencing technologies,  de novo sequencing has replaced the traditional method to become an important tool for exploring bacterial and fungal genomic structure, evolutionary genetic mechanism and key functions, contributing to a better understand of the role of bacterium in disease, agriculture and environment.

Application Region

1. Pathogen research: gene island annotation, virulence factor analysis

2. Drug resistance research: ARTB, CARD and other antibiotic resistance gene annotation, secreted protein research

3. Environmental adaptability research: carbohydrate enzyme annotation, transmembrane protein research, comparative genomics analysis

4. Fermentation engineering research: metabolic pathways, secondary metabolites


Data analysis Pipeline


Advantages and Application Areas

High production: We have complete over 500 projects, sequenced over 2,000 samples.
Quality service: We have introduced the latest High-throughput sequencing platform (Oxford Nanopore Technology) , the sequencing data are more accurate and lower cost, providing the customers with fast turnaround, and favorable prices. We have extensive project experience and Professional bioinformatic skills. We possess a complete annotation databases including KEGG, COG, Swiss-Prot, GO, TrEMBL, Pfam and Nr. We have professional Proprietary databases  including TCDB, PHI, ARDB, VFDB and CAZyme.


Biomarker Successful Cases

Date Article Title Periodical Influence Factor Sample 
2018

Comparative analysis of microbial fuel cell based biosensors developed

with a mixed culture and Shewanella loihica PV-4 and underlying biological mechanism

Bioresource technology 5.81 Shewanella loihica PV-4
2018

Genome sequencing and comparative genomics reveal

 the potential pathogenic mechanism of Cercospora sojina Hara on soybean

DNA research 5.42 Cercospora sojina Hara
2018

Combined Use of C. butyricum Sx-01 and L. salivarius C-1-3 Improves Intestinal Health

 and Reduces the Amount of Lipids in Serum via Modulation of Gut Microbiota in Mice

nutrients 4.19 C. butyricum Sx-01L. salivarius C-1-3
2016 Draft genome sequence of Acidithiobacillus ferrooxidans YQH-1 Genomics Data 3.91 Acidithiobacillus ferrooxidans YQH-1
2017

Plant growth-promoting effect and genomic analysis of the beneficial

 endophyte Streptomyces sp. KLBMP 5084 isolated from halophyte Limonium 北京赛车pk10投注sinense

Plant Soil 3.05 Streptomyces sp. KLBMP 5084
2015

Draft genome of iron-oxidizing bacterium Leptospirillum sp. YQP-1

 isolated from a volcanic lake in the Wudalianchi volcano, China

Genomics Data 2.91 Leptospirillum sp. YQP-1
2017

Complete genome sequence of endophyte Bacillus flexus KLBMP 4941

 reveals its plant growth promotion mechanism and genetic basis for salt tolerance

Journal of Biotechnology 2.59  Bacillus flexus KLBMP 4941
2018

Complete genome sequence of yam chlorotic necrosis 北京赛车pk10投注virus,

 a novel macluravirus infecting yam

Archives of Virology 2.16 Macluravirus
2019 Paracoccus indicus sp. nov., isolated from surface seawater in the Indian Ocean Antonie van Leeuwenhoek 2.09 Paracoccus indicus sp. Nov
2018 The complete genome sequence of Colwellia sp. NB097-1 reveals evidence for the potential genetic basis for its adaptation to cold environment Marine Genomics 1.97 Colwellia sp. NB097-1
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